Bioactive Peptides and Protein Hydrolysates as Lipoxygenase Inhibitors

Lipoxygenases are non-heme iron-containing enzymes that catalyze the oxidation of polyunsaturated fatty acids, resulting in production lipid hydroperoxides, which precursors inflammatory mediators. These widely distributed humans, other eukaryotes, and cyanobacteria. hold promise as therapeutic targets for several human diseases, including cancer inflammation-related disorders. Inhibitors lipoxygenase have potential applications pharmaceuticals, cosmetics, food. Bioactive peptides short amino acid sequences embedded within parent proteins, can be released by enzymatic hydrolysis, microbial fermentation, gastrointestinal digestion. A wide variety bioactivities been documented protein hydrolysates derived from different biological sources. Recent findings indicate both edible non-edible bioresources act inhibitors. This review aims to provide an overview current knowledge regarding anti-lipoxygenase millet grains, chia seeds, insects, milk fish feed, velvet antler blood, scales, feather keratins. The activities modes action these discussed. strengths shortcomings previous research this area emphasized. Additionally, directions areas improvement suggested accelerate discovery near future.